Ontology highlight
ABSTRACT:
SUBMITTER: Hansson O
PROVIDER: S-EPMC5766833 | biostudies-other | 2018 Jan
REPOSITORIES: biostudies-other
Alzheimer's & dementia : the journal of the Alzheimer's Association 20170715 1
<h4>Introduction</h4>It is hypothesized that cerebral hypoperfusion promotes the development of Alzheimer pathology. We therefore studied whether longstanding cerebral hypoperfusion is associated with Alzheimer pathology in nondemented humans.<h4>Methods</h4>Cerebral blood flow and amyloid β (<sup>18</sup>F-Flutemetamol) positron emission tomography retention were assessed in eleven patients with unilateral occlusion of precerebral arteries resulting in chronic and uneven hypoperfusion. A subset ...[more]