Ontology highlight
ABSTRACT:
SUBMITTER: Lin Y
PROVIDER: S-EPMC5767894 | biostudies-other | 2018 Jan
REPOSITORIES: biostudies-other
ACS medicinal chemistry letters 20171222 1
Using light as the sole stimulus and employing the generated singlet oxygen as a therapeutic agent and the trigger to activate chemo-drug release could serve as an elegant way to bring into full play the advantageous features of light and enhance therapeutic efficacy through a combination of chemotherapy and photodynamic therapy. Herein a liposomal drug system has been developed by embedding a fluorescent photosensitizer and a prodrug into phospholipid vesicles. Upon one- or two-photon light irr ...[more]