Ontology highlight
ABSTRACT:
SUBMITTER: Ghadersohi S
PROVIDER: S-EPMC5774623 | biostudies-other | 2017 Dec
REPOSITORIES: biostudies-other
Ghadersohi Saied S Tan Bruce K BK
Otolaryngologic clinics of North America 20170928 6
Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are chronic conditions causing nasal inflammation. CRS is increasingly recognized as a chronic inflammatory process rather than a chronic infection. Although the primary initiating factors in CRS remain unclear, AR is driven by IgE-mediated hypersensitivity to environmental allergens. Understanding the underlying inflammatory pathways and disease endotypes are driving innovation toward novel pharmacotherapies targeting critical mediators im ...[more]