Ontology highlight
ABSTRACT:
SUBMITTER: Tan JL
PROVIDER: S-EPMC5788876 | biostudies-other | 2018 Feb
REPOSITORIES: biostudies-other
Tan Jean L JL Lau Sin N SN Leaw Bryan B Nguyen Hong P T HPT Salamonsen Lois A LA Saad Mohamed I MI Chan Siow T ST Zhu Dandan D Krause Mirja M Kim Carla C Sievert William W Wallace Euan M EM Lim Rebecca R
Stem cells translational medicine 20180103 2
Idiopathic pulmonary fibrosis (IPF) is characterized by chronic inflammation, severe scarring, and stem cell senescence. Stem cell-based therapies modulate inflammatory and fibrogenic pathways by release of soluble factors. Stem cell-derived extracellular vesicles should be explored as a potential therapy for IPF. Human amnion epithelial cell-derived exosomes (hAEC Exo) were isolated and compared against human lung fibroblasts exosomes. hAEC Exo were assessed as a potential therapy for lung fibr ...[more]