Ontology highlight
ABSTRACT:
SUBMITTER: Nakagami H
PROVIDER: S-EPMC5809414 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Nakagami Hironori H Sugimoto Ken K Ishikawa Takahiro T Fujimoto Taku T Yamaoka Toshifumi T Hayashi Misa M Kiyohara Eiji E Ando Hiroshi H Terabe Yuta Y Takami Yoichi Y Yamamoto Koichi K Takeya Yasushi Y Takemoto Minoru M Koshizaka Masaya M Ebihara Tamotsu T Nakamura Ayumi A Nishikawa Mitsunori M Yao Xiang Jing XJ Hanaoka Hideki H Katayama Ichiro I Yokote Koutaro K Rakugi Hiromi H
NPJ aging and mechanisms of disease 20180213
SR-0379 is a functional peptide that has wound healing effect with anti-microbial action, making it an ideal drug to prevent infection. To evaluate the safety, efficacy, and pharmacokinetics of SR-0379 for the treatment of leg ulcers, a physician-initiated, phase I/IIa, first-in-patient clinical study was designed. A multi-center, double-blind, randomized clinical study was conducted from October 2015 to September 2016. The inclusion criteria for leg ulcers were (1) diabetes or critical limb isc ...[more]