Ontology highlight
ABSTRACT:
SUBMITTER: Lu C
PROVIDER: S-EPMC5852120 | biostudies-other | 2018 Mar
REPOSITORIES: biostudies-other
Lu Changqing C Dong Lihua L Zhou Hui H Li Qianmei Q Huang Guojiao G Bai Shu Jun SJ Liao Linchuan L
Scientific reports 20180314 1
Oligodendrocytes are the myelin-producing cells of the central nervous system (CNS). A variety of brain disorders from "classical" demyelinating diseases, such as multiple sclerosis, stroke, schizophrenia, depression, Down syndrome and autism, are shown myelination defects. Oligodendrocyte myelination is regulated by a complex interplay of intrinsic, epigenetic and extrinsic factors. Gpr17 (G protein-coupled receptor 17) is a G protein-coupled receptor, and has been identified to be a regulator ...[more]