Ontology highlight
ABSTRACT:
SUBMITTER: Coleman CB
PROVIDER: S-EPMC5853903 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Coleman Carrie B CB Daud Ibrahim I II Ogolla Sidney O SO Ritchie Julie A JA Smith Nicholas A NA Sumba Peter O PO Dent Arlene E AE Rochford Rosemary R
The Journal of infectious diseases 20170901 6
<h4>Background</h4>The 2 strains of Epstein-Barr virus (EBV), EBV type 1 (EBV-1) and EBV-2, differ in latency genes, suggesting that they use distinct mechanisms to establish latency. We previously reported that EBV-2 infects T cells in vitro. In this study, we tested the possibility that EBV-2 infects T cells in vivo.<h4>Methods</h4>Purified T-cell fractions isolated from children positive for EBV-1 or EBV-2 and their mothers were examined for the presence of EBV and for EBV type.<h4>Results</h ...[more]