Ontology highlight
ABSTRACT:
SUBMITTER: Bladen JC
PROVIDER: S-EPMC5856882 | biostudies-other | 2018 Apr
REPOSITORIES: biostudies-other
Bladen John C JC Moosajee Mariya M Tracey-White Dhani D Beaconsfield Michèle M O'Toole Edel A EA Philpott Michael P MP
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20180208 4
<h4>Purpose</h4>Sebaceous carcinoma (SC) is a clinical masquerader of benign conditions resulting in significant eye morbidity, sometimes leading to extensive surgical treatment including exenteration, and even mortality. Little is known about the genetic or molecular basis of SC. This study identifies the involvement of Hedgehog (Hh) signaling in periocular SC.<h4>Methods</h4>Fifteen patients with periocular SC patients were compared to 15 patients with eyelid nodular basal cell carcinoma (nBCC ...[more]