Ontology highlight
ABSTRACT:
SUBMITTER: Coscujuela Tarrero L
PROVIDER: S-EPMC5865691 | biostudies-other | 2018 Mar
REPOSITORIES: biostudies-other
Coscujuela Tarrero Lucia L Ferrero Giulio G Miano Valentina V De Intinis Carlo C Ricci Laura L Arigoni Maddalena M Riccardo Federica F Annaratone Laura L Castellano Isabella I Calogero Raffaele A RA Beccuti Marco M Cordero Francesca F De Bortoli Michele M
Oncotarget 20180219 18
Circular RNAs are highly stable molecules present in all eukaryotes generated by distinct transcript processing. We have exploited poly(A-) RNA-Seq data generated in our lab in MCF-7 breast cancer cells to define a compilation of exonic circRNAs more comprehensive than previously existing lists. Development of a novel computational tool, named <i>CircHunter</i>, allowed us to more accurately characterize circRNAs and to quantitatively evaluate their expression in publicly available RNA-Seq data ...[more]