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A Density-Driven Method for the Placement of Biological Cells Over Two-Dimensional Manifolds.

ABSTRACT: We introduce a graphical method originating from the computer graphics domain that is used for the arbitrary placement of cells over a two-dimensional manifold. Using a bitmap image whose luminance provides cell density, this method guarantees a discrete distribution of the positions of the cells respecting the local density. This method scales to any number of cells, allows one to specify arbitrary enclosing shapes and provides a scalable and versatile alternative to the more classical assumption of a uniform spatial distribution. The method is illustrated on a discrete homogeneous neural field, on the distribution of cones and rods in the retina and on the neural density of a flattened piece of cortex.

SUBMITTER: Rougier NP

PROVIDER: S-EPMC5869184 | biostudies-other | 2018

REPOSITORIES: biostudies-other

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A Density-Driven Method for the Placement of Biological Cells Over Two-Dimensional Manifolds.

Rougier Nicolas P NP

Frontiers in neuroinformatics 20180320

We introduce a graphical method originating from the computer graphics domain that is used for the arbitrary placement of cells over a two-dimensional manifold. Using a bitmap image whose luminance provides cell density, this method guarantees a discrete distribution of the positions of the cells respecting the local density. This method scales to any number of cells, allows one to specify arbitrary enclosing shapes and provides a scalable and versatile alternative to the more classical assumpti ...[more]

PMID: 29615887

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