Characterization of Ageing- and Diet-Related Swine Models of Sarcopenia and Sarcopenic Obesity.
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ABSTRACT:
SUBMITTER: Garcia-Contreras C
PROVIDER: S-EPMC5877684 | biostudies-other | 2018 Mar
REPOSITORIES: biostudies-other
Publications
Characterization of Ageing- and Diet-Related Swine Models of Sarcopenia and Sarcopenic Obesity.
Garcia-Contreras Consolacion C Vazquez-Gomez Marta M Torres-Rovira Laura L Gonzalez Jorge J Porrini Esteban E Gonzalez-Colaço Magali M Isabel Beatriz B Astiz Susana S Gonzalez-Bulnes Antonio A
International journal of molecular sciences 20180312 3
Sarcopenia and sarcopenic obesity are currently considered major global threats for health and well-being. However, there is a lack of adequate preclinical models for their study. The present trial evaluated the suitability of aged swine by determining changes in adiposity, fatty acids composition, antioxidant status and lipid peroxidation, development of metabolic disturbances and structural changes in tissues and organs. Iberian sows with clinical evidence of aging-related sarcopenia were fed ...[more]
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