Dataset Information

The Role of Cardiokines in Heart Diseases: Beneficial or Detrimental?

ABSTRACT: Cardiovascular disease remains the leading cause of morbidity and mortality, imposing a major disease burden worldwide. Therefore, there is an urgent need to identify new therapeutic targets. Recently, the concept that the heart acts as a secretory organ has attracted increasing attention. Proteins secreted by the heart are called cardiokines, and they play a critical physiological role in maintaining heart homeostasis or responding to myocardial damage and thereby influence the development of heart diseases. Given the critical role of cardiokines in heart disease, they might represent a promising therapeutic target. This review will focus on several cardiokines and discuss their roles in the pathogenesis of heart diseases and as potential therapeutics.

SUBMITTER: Wu YS

PROVIDER: S-EPMC5878913 | biostudies-other | 2018

REPOSITORIES: biostudies-other

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The Role of Cardiokines in Heart Diseases: Beneficial or Detrimental?

Wu Ye-Shun YS Zhu Bin B Luo Ai-Lin AL Yang Ling L Yang Chun C

BioMed research international 20180318

Cardiovascular disease remains the leading cause of morbidity and mortality, imposing a major disease burden worldwide. Therefore, there is an urgent need to identify new therapeutic targets. Recently, the concept that the heart acts as a secretory organ has attracted increasing attention. Proteins secreted by the heart are called cardiokines, and they play a critical physiological role in maintaining heart homeostasis or responding to myocardial damage and thereby influence the development of h ...[more]

PMID: 29744364

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Dataset Information

The Role of Cardiokines in Heart Diseases: Beneficial or Detrimental?

Publications

The Role of Cardiokines in Heart Diseases: Beneficial or Detrimental?

Similar Datasets

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