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Identification of new progestogen-associated networks in mammalian ovulation using bioinformatics.


ABSTRACT: Progesterone plays an essential role in mammalian ovulation. Although much is known about this process, the gene networks involved in ovulation have yet to be established. When analyze the mechanisms of ovulation, we often need to determine key genes or pathways to investigate the reproduction features. However, traditional experimental methods have a number of limitations.Data, in this study, were acquired from GSE41836 and GSE54584 which provided different samples. They were analyzed with the GEO2R and 546 differentially expressed genes were obtained from two data sets using bioinformatics (absolute log2 FC?>?1, P?

SUBMITTER: Yang F 

PROVIDER: S-EPMC5883354 | biostudies-other | 2018 Apr

REPOSITORIES: biostudies-other

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Identification of new progestogen-associated networks in mammalian ovulation using bioinformatics.

Yang Fang F   Wang Meng M   Zhang Baoyun B   Xiang Wei W   Zhang Ke K   Chu Mingxin M   Wang Pingqing P  

BMC systems biology 20180403 1


<h4>Background</h4>Progesterone plays an essential role in mammalian ovulation. Although much is known about this process, the gene networks involved in ovulation have yet to be established. When analyze the mechanisms of ovulation, we often need to determine key genes or pathways to investigate the reproduction features. However, traditional experimental methods have a number of limitations.<h4>Results</h4>Data, in this study, were acquired from GSE41836 and GSE54584 which provided different sa  ...[more]

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