Ontology highlight
ABSTRACT:
SUBMITTER: Rancz EA
PROVIDER: S-EPMC5886360 | biostudies-other | 2006 May
REPOSITORIES: biostudies-other
Rancz Ede A EA Häusser Michael M
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060501 20
Understanding the relationship between dendritic excitability and synaptic plasticity is vital for determining how dendrites regulate the input-output function of the neuron. Dendritic calcium spikes have been associated with the induction of long-term changes in synaptic efficacy. Here we use direct recordings from cerebellar Purkinje cell dendrites to show that synaptically activated local dendritic calcium spikes are potent triggers of cannabinoid release, producing a profound and short-term ...[more]