Ontology highlight
ABSTRACT:
SUBMITTER: Wleklinski M
PROVIDER: S-EPMC5887808 | biostudies-other | 2018 Feb
REPOSITORIES: biostudies-other
Wleklinski Michael M Loren Bradley P BP Ferreira Christina R CR Jaman Zinia Z Avramova Larisa L Sobreira Tiago J P TJP Thompson David H DH Cooks R Graham RG
Chemical science 20180104 6
We report the high throughput analysis of reaction mixture arrays using methods and data handling routines that were originally developed for biological tissue imaging. Desorption electrospray ionization (DESI) mass spectrometry (MS) is applied in a continuous on-line process at rates that approach 10<sup>4</sup> reactions per h at area densities of up to 1 spot per mm<sup>2</sup> (6144 spots per standard microtiter plate) with the sprayer moving at <i>ca.</i> 10<sup>4</sup> microns per s. Data ...[more]