Ontology highlight
ABSTRACT:
SUBMITTER: Ouchi M
PROVIDER: S-EPMC5887894 | biostudies-other | 2018 Apr
REPOSITORIES: biostudies-other
Diabetes, obesity & metabolism 20180108 4
An integrated analysis was performed with data from 4 phase 2 and phase 3 studies of tofogliflozin in which patients with type 2 diabetes mellitus received the sodium-glucose cotransporter 2 inhibitor tofogliflozin for up to 24 weeks. Sex differences, baseline haemoglobin A1c (HbA1c) and serum uric acid (UA) levels, and log<sub>10</sub> -transformed urinary N-acetyl-β-D-glucosaminidase ratio were significantly correlated with the reduction in serum UA levels at both 4 and 24 weeks in multivariat ...[more]