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N-terminal pro-B-type natriuretic peptide and microsize myocardial infarction risk in the reasons for geographic and racial differences in stroke study.

ABSTRACT: N-terminal pro B-type peptide (NT-proBNP) has been associated with risk of myocardial infarction (MI), but less is known about the relationship between NT-proBNP and very small non ST-elevation MI, also known as microsize MI. These events are now routinely detectable with modern troponin assays and are emerging as a large proportion of all MI. Here, we sought to compare the association of NT-proBNP with risk of incident typical MI and microsize MI in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.The REGARDS Study is a national cohort of 30,239 US community-dwelling black and white adults aged ??45 years recruited from 2003 to 2007. Expert-adjudicated outcomes included incident typical MI (definite/probable MI with peak troponin ??0.5 ?g/L), incident microsize MI (definite/probable MI with peak troponin

SUBMITTER: Sterling MR 

PROVIDER: S-EPMC5902876 | biostudies-other | 2018 Apr

REPOSITORIES: biostudies-other

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N-terminal pro-B-type natriuretic peptide and microsize myocardial infarction risk in the reasons for geographic and racial differences in stroke study.

Sterling Madeline R MR   Durant Raegan W RW   Bryan Joanna J   Levitan Emily B EB   Brown Todd M TM   Khodneva Yulia Y   Glasser Stephen P SP   Richman Joshua S JS   Howard George G   Cushman Mary M   Safford Monika M MM  

BMC cardiovascular disorders 20180416 1

<h4>Background</h4>N-terminal pro B-type peptide (NT-proBNP) has been associated with risk of myocardial infarction (MI), but less is known about the relationship between NT-proBNP and very small non ST-elevation MI, also known as microsize MI. These events are now routinely detectable with modern troponin assays and are emerging as a large proportion of all MI. Here, we sought to compare the association of NT-proBNP with risk of incident typical MI and microsize MI in the REasons for Geographic  ...[more]