Ontology highlight
ABSTRACT:
SUBMITTER: Cheng Z
PROVIDER: S-EPMC5903826 | biostudies-other | 2018 Feb
REPOSITORIES: biostudies-other
Experimental & molecular medicine 20180216 2
In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because of its high level of evolutionary conservation and its antisense orientation to the CASZ1 gene, which is vital for heart development. We explored the function of uc.4 in cells and in zebrafish, and describe a potential mechanism of action. P19 cells were used to investigate the function of uc.4 ...[more]