Ontology highlight
ABSTRACT:
SUBMITTER: Adler DH
PROVIDER: S-EPMC5910869 | biostudies-other | 2018 Apr
REPOSITORIES: biostudies-other
Adler Daniel H DH Wisse Laura E M LEM Ittyerah Ranjit R Pluta John B JB Ding Song-Lin SL Xie Long L Wang Jiancong J Kadivar Salmon S Robinson John L JL Schuck Theresa T Trojanowski John Q JQ Grossman Murray M Detre John A JA Elliott Mark A MA Toledo Jon B JB Liu Weixia W Pickup Stephen S Miller Michael I MI Das Sandhitsu R SR Wolk David A DA Yushkevich Paul A PA
Proceedings of the National Academy of Sciences of the United States of America 20180328 16
Although the hippocampus is one of the most studied structures in the human brain, limited quantitative data exist on its 3D organization, anatomical variability, and effects of disease on its subregions. Histological studies provide restricted reference information due to their 2D nature. In this paper, high-resolution (∼200 × 200 × 200 μm<sup>3</sup>) ex vivo MRI scans of 31 human hippocampal specimens are combined using a groupwise diffeomorphic registration approach into a 3D probabilistic a ...[more]