Ontology highlight
ABSTRACT:
SUBMITTER: Slamecka J
PROVIDER: S-EPMC5914882 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Slamecka Jaroslav J McClellan Steven S Wilk Anna A Laurini Javier J Manci Elizabeth E Hoerstrup Simon P SP Weber Benedikt B Owen Laurie L
Cell cycle (Georgetown, Tex.) 20180207 3
Fetal stem cells are a unique type of adult stem cells that have been suggested to be broadly multipotent with some features of pluripotency. Their clinical potential has been documented but their upgrade to full pluripotency could open up a wide range of cell-based therapies particularly suited for pediatric tissue engineering, longitudinal studies or disease modeling. Here we describe episomal reprogramming of mesenchymal stem cells from the human amnion to pluripotency (AM-iPSC) in chemically ...[more]