Advances in the drug therapies of acute myeloid leukemia (except acute wpromyelocytic leukemia).
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ABSTRACT:
SUBMITTER: Lin M
PROVIDER: S-EPMC5933364 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Publications
Advances in the drug therapies of acute myeloid leukemia (except acute wpromyelocytic leukemia).
Drug design, development and therapy 20180430
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy, characterized by the clonal expansion of myeloid blasts in the peripheral blood, bone marrow, and/or other tissues. The new drugs used for treating AML are facing a big challenge, and the candidates include cytotoxic drugs, targeted small-molecule inhibitors, and monoclonal antibodies. In recent years, active research has focused on several new agents for including them in the large antileukemic drug family. This review aims ...[more]
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