Ontology highlight
ABSTRACT:
SUBMITTER: Anasagasti A
PROVIDER: S-EPMC5939684 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Anasagasti Ander A Ezquerra-Inchausti Maitane M Barandika Olatz O Muñoz-Culla Maider M Caffarel María M MM Otaegui David D López de Munain Adolfo A Ruiz-Ederra Javier J
Investigative ophthalmology & visual science 20180501 6
<h4>Purpose</h4>The aim of this study was to identify differentially expressed microRNAs (miRNAs) that might play an important role in the etiology of retinal degeneration in a genetic mouse model of retinitis pigmentosa (rd10 mice) at initial stages of the disease.<h4>Methods</h4>miRNAs-mRNA interaction networks were generated for analysis of biological pathways involved in retinal degeneration.<h4>Results</h4>Of more than 1900 miRNAs analyzed, we selected 19 miRNAs on the basis of (1) a signif ...[more]