Ontology highlight
ABSTRACT:
SUBMITTER: Wang B
PROVIDER: S-EPMC5940889 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Wang Bo B Lucy Katie A KA Schuman Joel S JS Sigal Ian A IA Bilonick Richard A RA Lu Chen C Liu Jonathan J Grulkowski Ireneusz I Nadler Zachary Z Ishikawa Hiroshi H Kagemann Larry L Fujimoto James G JG Wollstein Gadi G
Scientific reports 20180508 1
The lamina cribrosa is a primary site of damage in glaucoma. While mechanical distortion is hypothesized to cause reduction of axoplasmic flow, little is known about how the pores, which contains the retinal ganglion cell axons, traverse the lamina cribrosa. We investigated lamina cribrosa pore paths in vivo to quantify differences in tortuosity of pore paths between healthy and glaucomatous eyes. We imaged 16 healthy, 23 glaucoma suspect and 48 glaucomatous eyes from 70 subjects using a swept s ...[more]