In vivo super-resolution imaging of transient retinal phototropism evoked by oblique light stimulation.
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ABSTRACT:
SUBMITTER: Lu Y
PROVIDER: S-EPMC5946809 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Publications
In vivo super-resolution imaging of transient retinal phototropism evoked by oblique light stimulation.
Lu Yiming Y Liu Changgeng C Yao Xincheng X
Journal of biomedical optics 20180501 5
Rod-dominated transient retinal phototropism (TRP) has been observed in freshly isolated retinas, promising a noninvasive biomarker for objective assessment of retinal physiology. However, in vivo mapping of TRP is challenging due to its subcellular signal magnitude and fast time course. We report here a virtually structured detection-based super-resolution ophthalmoscope to achieve subcellular spatial resolution and millisecond temporal resolution for in vivo imaging of TRP. Spatiotemporal prop ...[more]
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