Ontology highlight
ABSTRACT:
SUBMITTER: Mohagheghian E
PROVIDER: S-EPMC5951850 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Mohagheghian Erfan E Luo Junyu J Chen Junjian J Chaudhary Gaurav G Chen Junwei J Sun Jian J Ewoldt Randy H RH Wang Ning N
Nature communications 20180514 1
Increasing evidence shows that mechanical stresses are critical in regulating cell functions, fate, and diseases. However, no methods exist that can quantify isotropic compressive stresses. Here we describe fluorescent nanoparticle-labeled, monodisperse elastic microspheres made of Arg-Gly-Asp-conjugated alginate hydrogels (elastic round microgels, ERMGs). We generate 3D displacements and calculate strains and tractions exerted on an ERMG. Average compressive tractions on an ERMG are 570 Pa with ...[more]