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Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line.

ABSTRACT: This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the expression of endogenous Hu proteins is presented.

SUBMITTER: Ardelt A 

PROVIDER: S-EPMC5972843 | biostudies-other | 2018 Feb

REPOSITORIES: biostudies-other

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Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line.

Ardelt A A   Carpenter R R   Iwuchukwu I I   Zhang A A   Lin W W   Kosciuczuk E E   Hinkson C C   Rebeiz T T   Reitz S S   King P P  

Data in brief 20171017

This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the expression of endogenous Hu proteins is presented. ...[more]