Ontology highlight
ABSTRACT:
SUBMITTER: Yang ZL
PROVIDER: S-EPMC5980201 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Yang Zhen Lu ZL Tian Wei W Wang Qing Q Zhao Ying Y Zhang Yun Lei YL Tian Ying Y Tang Yu Xia YX Wang Shou Ju SJ Liu Ying Y Ni Qian Qian QQ Lu Guang Ming GM Teng Zhao Gang ZG Zhang Long Jiang LJ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20180222 5
Oxygen (O<sub>2</sub>) plays a critical role during photodynamic therapy (PDT), however, hypoxia is quite common in most solid tumors, which limits the PDT efficacy and promotes the tumor aggression. Here, a safe and multifunctional oxygen-evolving nanoplatform is costructured to overcome this problem. It is composed of a prussian blue (PB) core and chlorin e6 (Ce6) anchored periodic mesoporous organosilica (PMO) shell (denoted as PB@PMO-Ce6). In the highly integrated nanoplatform, the PB with c ...[more]