Ontology highlight
ABSTRACT:
SUBMITTER: Yang W
PROVIDER: S-EPMC5983804 | biostudies-other | 2018 Apr
REPOSITORIES: biostudies-other
Yang Weili W Chen Ji J Meng Yuhong Y Chen Zhenzhen Z Yang Jichun J
International journal of molecular sciences 20180426 5
Liver ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver transplantation, and other liver surgeries. It is one of the leading causes for post-surgery hepatic dysfunction, always leading to morbidity and mortality. Several strategies, such as low-temperature reperfusion and ischemic preconditioning, are useful for ameliorating liver IRI in animal models. However, these methods are difficult to perform in clinical surgeries. It has been reported that the activati ...[more]