Ontology highlight
ABSTRACT:
SUBMITTER: Maggi S
PROVIDER: S-EPMC5992197 | biostudies-other | 2018 Jun
REPOSITORIES: biostudies-other
Maggi Silvia S Peyrache Adrien A Humphries Mark D MD
Nature communications 20180607 1
The prefrontal cortex is implicated in learning the rules of an environment through trial and error. But it is unclear how such learning is related to the prefrontal cortex's role in short-term memory. Here we ask if the encoding of short-term memory in prefrontal cortex is used by rats learning decision rules in a Y-maze task. We find that a similar pattern of neural ensemble activity is selectively recalled after reinforcement for a correct decision. This reinforcement-selective recall only re ...[more]