Ontology highlight
ABSTRACT:
SUBMITTER: Li H
PROVIDER: S-EPMC5992882 | biostudies-other | 2018 Jun
REPOSITORIES: biostudies-other
Li Hui H Wei Xuefeng X Yang Jiameng J Dong Dong D Hao Dan D Huang Yongzhen Y Lan Xianyong X Plath Martin M Lei Chuzhao C Ma Yun Y Lin Fengpeng F Bai Yueyu Y Chen Hong H
Molecular therapy. Nucleic acids 20180306
Muscle development is regulated under a series of complicate processes, and non-coding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), have been reported to play important roles in regulating myoblast proliferation and differentiation. We found that miR-107 expression was high in skeletal muscle of Qinchuan cattle. Overexpression of miR-107 inhibited bovine myoblasts differentiation and protected cells from apoptosis. Wnt3a was identified as a target of miR-107 by luciferase activ ...[more]