Ontology highlight
ABSTRACT:
SUBMITTER: Prandina A
PROVIDER: S-EPMC6009883 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Journal of enzyme inhibition and medicinal chemistry 20181201 1
Phenazine is known to regroup planar nitrogen-containing heterocyclic compounds. It was used here to enhance the bioavailability of the biologically important compound iodinin, which is near insoluble in aqueous solutions. Its water solubility has led to the development of new formulations using diverse amphiphilic α-cyclodextrins (CDs). With the per-[6-desoxy-6-(3-perfluorohexylpropanethio)-2,3-di-O-methyl]-α-CD, we succeeded to get iodinin-loaded nanoformulations with good parameters such as a ...[more]