Ontology highlight
ABSTRACT:
SUBMITTER: Fu J
PROVIDER: S-EPMC6018854 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Fu Jingjing J Gao Junwei J Gong Linji L Ma Yuanyuan Y Xu Haiwei H Gu Zhanjun Z Zhu Jingci J Fan Xiaotang X
International journal of nanomedicine 20180622
<h4>Introduction</h4>Silica nanoparticles (SiO<sub>2</sub>-NPs) are currently among the most widely used nanomaterials, but their potentially adverse effects on brain development remain unknown. The developing brain is extremely sensitive to NP neurotoxicity during the early postnatal period.<h4>Materials and methods</h4>Herein, we investigated the effects of SiO<sub>2</sub>-NPs (doses of 10, 20, or 50 mg with a particle size of ~91 nm, equivalent to aerosol mass concentrations 55.56, 111.11, an ...[more]