Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women.
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ABSTRACT:
SUBMITTER: Roelfsema F
PROVIDER: S-EPMC6030831 | biostudies-other | 2018 Jul
REPOSITORIES: biostudies-other
Publications
Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women.
Roelfsema Ferdinand F Yang Rebecca J RJ Veldhuis Johannes D JD
Journal of the Endocrine Society 20180614 7
<h4>Context</h4>Controlled, blinded studies of sex-hormone replacement in postmenopausal women using natural estradiol (E<sub>2</sub>) and native progesterone (P) are few.<h4>Objective</h4>To delineate the effect of E<sub>2</sub> alone or with P on lipids and inflammatory markers.<h4>Design</h4>A placebo-controlled, double-masked, prospectively randomized study of 40 healthy, postmenopausal volunteers assigned to four treatment groups: placebo, intramuscular E<sub>2</sub>, and/or micronized oral ...[more]
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