Ontology highlight
ABSTRACT:
SUBMITTER: Rossetti RAM
PROVIDER: S-EPMC6033398 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Rossetti Renata Ariza Marques RAM Lorenzi Noely Paula Cristina NPC Yokochi Kaori K Rosa Maria Beatriz Sartor de Faria MBSF Benevides Luciana L Margarido Paulo Francisco Ramos PFR Baracat Edmund Chada EC Carvalho Jesus Paula JP Villa Luisa Lina LL Lepique Ana Paula AP
PloS one 20180705 7
Immune evasion by tumors includes several different mechanisms, including the inefficiency of antigen presenting cells (APCs) to trigger anti-tumor T cell responses. B lymphocytes may display a pro-tumoral role but can also be modulated to function as antigen presenting cells to T lymphocytes, capable of triggering anti-cancer immune responses. While dendritic cells, DCs, are the best APC population to activate naive T cells, DCs or their precursors, monocytes, are frequently modulated by tumors ...[more]