The Novel Biomarker of Germ Cell Tumours, Micro-RNA-371a-3p, Has a Very Rapid Decay in Patients with Clinical Stage 1.
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ABSTRACT:
SUBMITTER: Radtke A
PROVIDER: S-EPMC6039090 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Publications
The Novel Biomarker of Germ Cell Tumours, Micro-RNA-371a-3p, Has a Very Rapid Decay in Patients with Clinical Stage 1.
Radtke Arlo A Hennig Finja F Ikogho Raphael R Hammel Johannes J Anheuser Petra P Wülfing Christian C Belge Gazanfer G Dieckmann Klaus-Peter KP
Urologia internationalis 20180426 4
<h4>Background</h4>Accumulating evidence suggests serum levels of microRNA (miR)-371a-3p to be a novel tumour marker of testicular germ cell tumours (GCTs). Presently, there is only limited information regarding the velocity of decline of serum levels in response to treatment.<h4>Patients and methods</h4>Twenty-four patients with testicular GCT (20 seminoma, 4 nonseminoma, median age 40 years) with clinical stage 1 had measurements of serum levels of miR-371a-3p preoperatively and repeatedly on ...[more]
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