Ontology highlight
ABSTRACT:
SUBMITTER: Jaskiewicz JJ
PROVIDER: S-EPMC6056504 | biostudies-other | 2018 Jul
REPOSITORIES: biostudies-other
Nature communications 20180723 1
Cryptosporidiosis in an enteric infection caused by Cryptosporidium parasites and is a major cause of acute infant diarrhea in the developing world. A major bottleneck to research progress is the lack of methods to cryopreserve Cryptosporidium oocysts, thus requiring routine propagation in laboratory animals. Here, we report a method to cryopreserve C. parvum oocysts by ultra-fast cooling. Cryopreserved oocysts exhibit high viability and robust in vitro excystation, and are infectious to interfe ...[more]