Dataset Information

Novel evaluation scale for QOL (QOL-ACD-BP) in preoperative chemotherapy for breast cancer.

ABSTRACT: Quality-of-life (QOL) has been reported to affect the prognosis of many types of cancer, and several studies used various QOL assessment tools to determine the relationship between QOL and cancer prognosis. In this study, QOL-Questionnaire for Cancer Patients Treated with Anti-Cancer Drugs-the Breast (QOL-ACD-B) was modified to be suitable for preoperative chemotherapy (POC) and was named the QOL-ACD-BP.A total of 300 patients were treated with POC after being diagnosed with breast cancer between February 2007 and December 2016 at our institute. We evaluated novel evaluation scale for QOL (QOL-ACD-BP) before and after POC in a retrospective manner.In the multivariate analysis with overall survival, the high QOL before [p?=?0.048, hazard ratio (HR) 0.441] or after POC (p?=?0.030, HR 0.273) was an independent factor.Our study shows that QOL after POC may also affect prognosis and supported the importance of maintaining QOL in cancer treatment. In patients with breast cancer treated with POC, QOL-ACD-BP, which is a new QOL evaluation index, was found to be a useful tool for predicting the patients' prognosis.

SUBMITTER: Takada K

PROVIDER: S-EPMC6061048 | biostudies-other | 2018 Aug

REPOSITORIES: biostudies-other

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Novel evaluation scale for QOL (QOL-ACD-BP) in preoperative chemotherapy for breast cancer.

Takada Koji K Kashiwagi Shinichiro S Goto Wataru W Asano Yuka Y Takahashi Katsuyuki K Morisaki Tamami T Takashima Tsutomu T Tomita Shuhei S Hirakawa Kosei K Ohira Masaichi M

Journal of cancer research and clinical oncology 20180519 8

<h4>Purpose</h4>Quality-of-life (QOL) has been reported to affect the prognosis of many types of cancer, and several studies used various QOL assessment tools to determine the relationship between QOL and cancer prognosis. In this study, QOL-Questionnaire for Cancer Patients Treated with Anti-Cancer Drugs-the Breast (QOL-ACD-B) was modified to be suitable for preoperative chemotherapy (POC) and was named the QOL-ACD-BP.<h4>Methods</h4>A total of 300 patients were treated with POC after being dia ...[more]

PMID: 29779135

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Dataset Information

Novel evaluation scale for QOL (QOL-ACD-BP) in preoperative chemotherapy for breast cancer.

Publications

Novel evaluation scale for QOL (QOL-ACD-BP) in preoperative chemotherapy for breast cancer.

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