Dataset Information

Influence of Hip Abductor Strength on Functional Outcomes Before and After Total Knee Arthroplasty: Post Hoc Analysis of a Randomized Controlled Trial.

ABSTRACT: Total knee arthroplasty (TKA) is associated with declines in hip abductor (HA) muscle strength; however, a longitudinal analysis demonstrating the influence of TKA on trajectories of HA strength change has not been conducted.The purpose of this study was to quantify changes in HA strength from pre-TKA through 3 months post-TKA and to characterize the relationship between HA strength changes and physical performance.This study is a post hoc analysis of a randomized controlled trial.Data from 162 participants (89 women, mean age = 63 y) were used for analysis. Data were collected by masked assessors preoperatively and at 1 and 3 months following surgery. Outcomes included: Timed "Up and Go" test (TUG), Stair Climbing Test (SCT), Six-Minute Walk Test (6MWT), and walking speed. Paired t tests were used for between- and within-limb comparisons of HA strength. Multivariable regression was used to determine contributions of independent variables, HA and knee extensor strength, to the dependent variables of TUG, SCT, 6MWT, and walking speed at each time point.Hip abductor strength was significantly lower in the surgical limb pre-TKA (mean = 0.015; 95% CI = 0.010-0.020), 1 month post-TKA (0.028; 0.023-0.034), and 3 months post-TKA (0.02; 0.014-0.025) compared with the nonsurgical limb. Hip abductor strength declined from pre-TKA to 1 month post-TKA (18%), but not at the 3-month time point (0%). Hip abductor strength independently contributed to performance-based outcomes pre-TKA; however, this contribution was not observed post-TKA.The post hoc analysis prevents examining all outcomes likely to be influenced by HA strength.Surgical limb HA strength is impaired prior to TKA, and worsens following surgery. Furthermore, HA strength contributes to performance-based outcomes, supporting the hypothesis that HA strength influences functional recovery.

SUBMITTER: Loyd BJ

PROVIDER: S-EPMC6074832 | biostudies-other | 2017 Sep

REPOSITORIES: biostudies-other

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Influence of Hip Abductor Strength on Functional Outcomes Before and After Total Knee Arthroplasty: Post Hoc Analysis of a Randomized Controlled Trial.

Loyd Brian J BJ Jennings Jason M JM Judd Dana L DL Kim Raymond H RH Wolfe Pamela P Dennis Douglas A DA Stevens-Lapsley Jennifer E JE

Physical therapy 20170901 9

<h4>Background</h4>Total knee arthroplasty (TKA) is associated with declines in hip abductor (HA) muscle strength; however, a longitudinal analysis demonstrating the influence of TKA on trajectories of HA strength change has not been conducted.<h4>Objective</h4>The purpose of this study was to quantify changes in HA strength from pre-TKA through 3 months post-TKA and to characterize the relationship between HA strength changes and physical performance.<h4>Design</h4>This study is a post hoc anal ...[more]

PMID: 28969350

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Project description:BackgroundBecause people with total knee arthroplasty (TKA) have persistent functional limitations and disability, identifying modifiable risk factors for persistent disability is warranted. Before surgery, people have pervasive lower extremity muscle weakness. The fact that hip abductor muscle strength is often not targeted in postoperative rehabilitation may contribute to functional limitations.ObjectiveStudy objectives were: (1) to examine the reliability of handheld dynamometry (HHD) for measuring hip abductor strength and (2) to determine whether hip abductor strength contributes to physical function beyond the contribution of quadriceps muscle strength.DesignThis was a cross-sectional study.MethodsTwo-hundred ten participants underwent quadriceps and hip abductor muscle strength testing and measurement of physical function (performance-based and self-reported outcomes). Correlation and regression equations were built to determine the relationships of strength, pain, and functional ability. A subset of 16 participants underwent hip abductor strength testing at 2 sessions to determine the reliability of the measure.ResultsMeasuring hip abductor strength with HHD yielded excellent relative reliability, with an intraclass correlation coefficient (ICC [2,3]) of .95 and a 95% confidence interval of .86 to .98, but moderate absolute reliability, with a minimal detectable change (with 95% confidence) of 47.6 N and a 95% confidence interval of 35.5 to 76.5. Hip abductor strength made a significant additional contribution to performance-based measures of physical function after anthropometric covariates and quadriceps muscle strength were accounted for. Hip abductor strength did not show bivariate correlations with patient-reported measures of physical function and did not contribute to patient-reported physical function after covariates and quadriceps muscle strength were accounted for.LimitationsA cause-and-effect relationship between hip abductor strength and physical function could not be established.ConclusionsIn people with unilateral TKA, HHD testing of hip abductor strength is reliable. Hip abductor strength contributes to performance-based but not patient-reported measures of physical function in people with unilateral TKA.

Project description:BACKGROUND:Patients with knee osteoarthritis (OA) report knee pain, limitation in physical activities and low quality of life. The two primary treatments for knee OA are non-surgical treatment (e.g., exercise) and surgery (total knee arthroplasty (TKA)); however, national guidelines recommend non-surgical treatment to be tried prior to surgical procedures. Patients with knee OA are characterized by decreased muscle strength, particularly in the knee-extensor muscles. Correspondingly, decreased knee-extensor strength is found to be associated with an increased risk of development, progression and severity of knee OA symptoms. Recent trials suggest a positive effect of pre-operative exercise on pre- and post-operative outcome; however, the most effective pre-operative knee-extensor strength exercise dosage is not known. The purpose of the present trial is to investigate the efficacy of three different exercise dosages of pre-operative, home-based, knee-extensor strength exercise on knee-extensor strength before and shortly after surgery in patients eligible for TKA due to end-stage knee OA. METHODS:In this randomized dose-response trial with a three-arm parallel design, 140 patients with end-stage knee OA (candidates for TKA) are randomized to one of three exercise dosages (two, four or six session/week) of knee-extensor strength exercise (three sets, 12 repetitions at 12 RM, per exercise session) for 12 weeks. The knee-extensor strength exercise is home-based (unsupervised) and performed with an elastic exercise band following an initial exercise instruction. Adherence is objectively quantified using a sensor attached to the exercise band. The primary outcome will be the change in knee-extensor strength. Following the 12-week exercise period, the need for TKA surgery is re-assessed by an orthopedic surgeon. DISCUSSION:Decreased knee-extensor strength is a major challenge in patients with knee OA. Exercise programs focusing on knee-extensor strength are found to be more effective in relieving knee OA pain and symptoms compared to more general exercise programs. However, the optimal exercise dosage for knee-extensor strength deficits in patients with knee OA is inconclusive. Knowledge on the dose-response relationship for knee-extensor strength exercise in patients with knee OA will help guide future non-surgical treatment in this patient population. TRIAL REGISTRATION:ClinicalTrials.gov, ID: NCT02931058 . Pre-registered on 10 October 2016.

Dataset Information

Influence of Hip Abductor Strength on Functional Outcomes Before and After Total Knee Arthroplasty: Post Hoc Analysis of a Randomized Controlled Trial.

Publications

Influence of Hip Abductor Strength on Functional Outcomes Before and After Total Knee Arthroplasty: Post Hoc Analysis of a Randomized Controlled Trial.

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