Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats.
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ABSTRACT:
SUBMITTER: Budriesi R
PROVIDER: S-EPMC6078294 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Publications
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats.
Budriesi Roberta R Vivarelli Fabio F Canistro Donatella D Aldini Rita R Babot Marquillas Clara C Corazza Ivan I Fato Romana R Cirillo Silvia S Bergamini Christian C D'Errico Antonia A Bolchi Cristiano C Cevenini Monica M Degiovanni Alessio A Frosini Maria M Camarda Luca L Chiarini Alberto A Micucci Matteo M
PloS one 20180806 8
The effects of Castanea sativa Mill. have been studied in high fat diet (HFD) overweight rats. Natural Extract of Chestnut bark (Castanea sativa Mill.) (ENC®), rich in ellagitannins, has been studied in 120 male Sprague-Dawley rats, divided in four groups. Two groups were controls: regular (RD) and HDF diet. Two groups received ENC® (20 mg/kg/day): RD + ENC® and HFD + ENC®. At baseline and at 7, 14 and 21 days, weight gain, serum lipids, plasma cytokines, liver histology, microsomial enzymes and ...[more]
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