Ontology highlight
ABSTRACT:
SUBMITTER: Cheng Z
PROVIDER: S-EPMC6082852 | biostudies-other | 2018 Aug
REPOSITORIES: biostudies-other
Cheng Zhangjun Z Liu Lei L Zhang Xue-Jun XJ Lu Miao M Wang Yang Y Assfalg Volker V Laschinger Melanie M von Figura Guido G Sunami Yoshiaki Y Michalski Christoph W CW Kleeff Jörg J Friess Helmut H Hartmann Daniel D Hüser Norbert N
Scientific reports 20180808 1
Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a nuclear receptor demonstrated to play an important role in various biological processes. The aim of this study was to determine the effect of PPARγ on liver regeneration upon partial hepatectomy (PH) in mice. Mice were subjected to two-thirds PH. Before surgery, mice were either treated with the PPARγ agonist rosiglitazone, the PPARγ antagonist GW9662 alone, or with the c-met inhibitor SGX523. Liver-to-body-weight ratio, lab values, a ...[more]