Ontology highlight
ABSTRACT:
SUBMITTER: Zhang M
PROVIDER: S-EPMC6084312 | biostudies-other | 2017 Nov
REPOSITORIES: biostudies-other
Zhang Mingzi M Ahn Woosung W Kim Sumin S Hong Hyun Sook HS Quan Chengshi C Son Youngsook Y
Microcirculation (New York, N.Y. : 1994) 20171101 8
<h4>Objective</h4>The aim of this study was to evaluate the angiogenicity of a combination of BM-EPCs and BM-MSCs in vitro in the presence of SP and its working mechanism.<h4>Methods</h4>BM-MSCs and BM-EPCs were cocultured with or without SP. ELISA and RT-PCR were performed to detect angiogenic factors such as VEGF and PDGF-BB. N-cadherin was detected by Western blot analysis. The tubular network-forming ability was evaluated by a Matrigel tube-forming assay.<h4>Results</h4>BM-EPCs coculture wit ...[more]