Applying dynamic contrast enhanced MSOT imaging to intratumoral pharmacokinetic modeling.
Ontology highlight
ABSTRACT:
SUBMITTER: Xiao TG
PROVIDER: S-EPMC6086408 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
Publications
Applying dynamic contrast enhanced MSOT imaging to intratumoral pharmacokinetic modeling.
Xiao Ted G TG Weis Jared A JA Gayzik F Scott FS Thomas Alexandra A Chiba Akiko A Gurcan Metin N MN Topaloglu Umit U Samykutty Abhilash A McNally Lacey R LR
Photoacoustics 20180727
Examining the dynamics of an agent in the tumor microenvironment can offer critical insights to the influx rate and accumulation of the agent. Intratumoral kinetic characterization in the <i>in vivo</i> setting can further elicudate distribution patterns and tumor microenvironment. Dynamic contrast-enhanced Multispectral Optoacoustic Tomographic imaging (DCE-MSOT) acquires serial MSOT images with the administration of an exogenous contrast agent over time. We tracked the dynamics of a tumor-targ ...[more]
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