Ontology highlight
ABSTRACT:
SUBMITTER: Baigger A
PROVIDER: S-EPMC6111809 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
Baigger Anja A Eicke Dorothee D Yuzefovych Yuliia Y Pogozhykh Denys D Blasczyk Rainer R Figueiredo Constanca C
Journal of cellular and molecular medicine 20180612 9
Recently, platelet-derived growth factors present in lysates became an extreme interest in the field of regenerative medicine such as in wound healing and as substitutes to foetal bovine serum in xeno-free cell culture systems. However, the generation of such platelet lysates completely depends on the availability of platelet donors. In this study, the possibility to use in vitro-generated megakaryocytes derived from induced pluripotent stem cells (iPSCs) as a cell source for typical platelet gr ...[more]