Ontology highlight
ABSTRACT:
SUBMITTER: Han J
PROVIDER: S-EPMC6111825 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
Han Junwei J Liu Siyao S Jiang Ying Y Xu Chaohan C Zheng Baotong B Jiang Minghao M Yang Haixiu H Su Fei F Li Chunquan C Zhang Yunpeng Y
Journal of cellular and molecular medicine 20180704 9
Breast cancer is one of the most deadly forms of cancer in women worldwide. Better prediction of breast cancer prognosis is essential for more personalized treatment. In this study, we aimed to infer patient-specific subpathway activities to reveal a functional signature associated with the prognosis of patients with breast cancer. We integrated pathway structure with gene expression data to construct patient-specific subpathway activity profiles using a greedy search algorithm. A four-subpathwa ...[more]