Ontology highlight
ABSTRACT:
SUBMITTER: Luo J
PROVIDER: S-EPMC6111875 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
Luo Jintai J Zhao Shankun S Wang Jiamin J Luo Lianmin L Li Ermao E Zhu Zhiguo Z Liu Yangzhou Y Kang Ran R Zhao Zhigang Z
Journal of cellular and molecular medicine 20180711 9
With no effective therapy to prevent or treat ureteral stricture (US), a multifactorial fibrotic disease after iatrogenic injury of the ureter, the need for new therapies is urgent. Mesenchymal stem cells (MSCs) have been widely studied for treating tissue defects and excessive fibrosis, and recent studies established that one of the main therapeutic vectors of MSCs is comprised in their secretome and represented by extracellular vesicles (EVs). Thus, we have determined to explore the specific r ...[more]