Bioactive nano-metal-organic frameworks as antimicrobials against Gram-positive and Gram-negative bacteria.
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ABSTRACT:
SUBMITTER: Bhardwaj N
PROVIDER: S-EPMC6116815 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
Publications
Bioactive nano-metal-organic frameworks as antimicrobials against Gram-positive and Gram-negative bacteria.
Bhardwaj Neha N Pandey Satish K SK Mehta Jyotsana J Bhardwaj Sanjeev K SK Kim Ki-Hyun KH Deep Akash A
Toxicology research 20180511 5
More effective antibiotics are needed to overcome the problem of multidrug resistance. The antibacterial efficacies of three Zn-based nano metal-organic frameworks (nMOFs) - IRMOF-3, MOF-5, and Zn-BTC - were explored, both alone and as mixtures with ampicillin and kanamycin. When tested against <i>Escherichia coli</i>, <i>Staphylococcus aureus</i>, <i>Staphylococcus lentus</i>, and <i>Listeria monocytogenes</i>, the nMOF/drug mixtures demonstrated synergistic (IRMOF-3/kanamycin) or additive (oth ...[more]
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