Ontology highlight
ABSTRACT:
SUBMITTER: Bi J
PROVIDER: S-EPMC6128440 | biostudies-other | 2018 Aug
REPOSITORIES: biostudies-other
Aging 20180801 8
Circ-BPTF (hsa_circ_0000799) is a novel circular RNA derived from BPTF exons. Although BPTF is a well-studied predecessor gene, the characteristics and functions of circ-BPTF have not yet been reported. Here, we show that expression of circ-BPTF is increased in bladder cancer (BCa) tissues and cell lines compared with noncancerous tissues and cell lines. Consistently, BCa patients with higher expression levels of circ-BPTF were found to have higher tumor grades and poorer prognosis. Functionally ...[more]