Ontology highlight
ABSTRACT:
SUBMITTER: Sugimachi K
PROVIDER: S-EPMC6134007 | biostudies-other | 2018 Aug
REPOSITORIES: biostudies-other
Sugimachi Keishi K Sakimura Shotaro S Kuramitsu Shotaro S Hirata Hidenari H Niida Atsushi A Iguchi Tomohiro T Eguchi Hidetoshi H Masuda Takaaki T Morita Masaru M Toh Yasushi Y Maehara Yoshihiko Y Suzuki Yutaka Y Mimori Koshi K
British journal of cancer 20180803 4
<h4>Background</h4>We aim to investigate the utility of serial gene mutation tracking for locally advanced CRC in those who underwent curative resection following neoadjuvant chemotherapy.<h4>Methods</h4>We prospectively collected 10 locally advanced CRC cases for which curative resection was performed following preoperative neoadjuvant chemotherapy. Tissues from the primary tumour, distant metastatic tumours, and blood plasma were obtained during serial treatment. Comprehensive mutation analysi ...[more]