Ontology highlight
ABSTRACT:
SUBMITTER: Church JA
PROVIDER: S-EPMC6136084 | biostudies-other | 2018 Jul
REPOSITORIES: biostudies-other
Church James A JA Parker Edward Pk EP Kosek Margaret N MN Kang Gagandeep G Grassly Nicholas C NC Kelly Paul P Prendergast Andrew J AJ
Future microbiology 20180621
Oral vaccines significantly underperform in low-income countries. One possible contributory factor is environmental enteric dysfunction (EED), a subclinical disorder of small intestinal structure and function among children living in poverty. Here, we review studies describing oral vaccine responses and EED. We identified eight studies evaluating EED and oral vaccine responses. There was substantial heterogeneity in study design and few consistent trends emerged. Four studies reported a negative ...[more]