Ontology highlight
ABSTRACT:
SUBMITTER: Darbari DS
PROVIDER: S-EPMC6142608 | biostudies-other | 2017 Dec
REPOSITORIES: biostudies-other
Darbari Deepika S DS Brandow Amanda M AM
Hematology. American Society of Hematology. Education Program 20171201 1
Pain is a complex multidimensional experience and the most common morbidity in patients with sickle cell disease (SCD). Tools to assess pain can be of use not only to guide pain treatment but also to provide insight into underlying pain neurobiology. Mechanisms of pain in SCD are multifactorial and are not completely elucidated. Although vaso-occlusion of microcirculation by sickled red cells is believed to be the underlying mechanism of acute vaso-occlusive pain, mechanisms for chronic pain and ...[more]